types of titanium dioxide manufacturer

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Scientists analyzed research that examined how titanium dioxide nanoparticles interact with the brain for a 2015 review published in Nanoscale Research Letters. The researchers wrote: “Once the TiO2 NPs are translocated into the central nervous system through [certain] pathways, they may accumulate in the brain regions. For their slow elimination rates, those NPs could remain in the brain zones for a long period, and the Ti contents would gradually increase with repeated exposure.” After reviewing dozens of studies, the scientists concluded: “Long-term or chronic exposure to TiO2 nanoparticles could potentially lead to the gradually increased Ti contents in the brain, which may eventually induce impairments on the neurons and glial cells and lead to CNS dysfunction as a consequence.”

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Historically, the first mentions of zinc sulfide being utilized as a pigment were approximately sixty years before the everyday use of lithopone. Originally, it was thought to be appropriate for coloring rubber. In England, a patent was granted for this process. Two decades after this, the focus shifted to zinc sulfide as a suitable pigment for paint. The year 1874 witnessed the patenting of a manufacturing process for a novel white pigment composed of zinc sulfide and barium sulfate. Dubbed Charlton white or Orr’s white enamel, this began a new era for white pigments.

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Titanium dioxide, also known as TiO2, is a widely used pigment and catalyst in various industries. It's renowned for its exceptional brightness, high refractive index, and excellent chemical stability. Due to these properties, TiO2 has found extensive applications in paints, plastics, papers, inks, food colorants, sunscreens, and more. As demand for this versatile material grows, understanding the landscape of TiO2 manufacturers becomes increasingly important.

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A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”

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